New generation cosmeceutical ingredient for sensitive skin

Approximately 40% of the population, of all categories and phototypes, complains of having sensitive skin. Sensitive skin is healthy but over-responsive. Currently all of the causes for this are not known yet, but an increase of the permeability of the stratum corneum as well as an exaggeration of the nerve response are considered to be involved in the phenomenon of sensitive skin.

Laboratoires Sérobiologiques has developed a pure tetrapeptide based on a new mechanism of action, mainly targeting neurosensitive skin, able to reduce the nerve response to external stimuli: Skinasensyl™

• Pure tetrapeptide targeting over-reactive skin by:
          - a decrease of the release of pro-inflammatory neuromediators (CGRP),
          - a reduction of the response of the sensory nerve fibers to external stimuli,
          - via its binding to the μ opioid receptor on nerve endings.
• Increase of the skin's tolerance threshold.
• Reduction of sensations of pain and discomfort, perceived by the end-users.

For a soothing and "pain killer" effect on the skin

The tolerance threshold of skin is increased, skin is less reactive to different stimuli and sensations of pain and discomfort are diminished.

This development is especially relevant taking into consideration the growing demand for cosmeceutical products and "home-use" treatments with effects similar to dermatological procedures, such as microdermabrasion and peels. While becoming increasingly targeted and 'smart', recent skin care products may tend to generate discomfort on very sensitive skin. To allow sensitive skin to benefit from these performing ingredients and treatments without any restriction, it was necessary to develop an active to boost its tolerance... mission accomplished with SKINASENSYL™, the first soothing cosmeceutical active which offers sensitive skin the latest advances in cosmetic research.